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About Us : Biographies : Mr John Davies

John Hugh Davies

GMC Registration: 2625133

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Qualifications
Prizes & Awards
Current Appointments
Previous Appointments
Surgical courses attended
Publications
Presentations
Abstracts

John Davies attended Bishop Gore School, Swansea and studied medicine at St Bartholomew’s Hospital Medical School, London. During his undergraduate training he attained a BSc (Hons) degree in Pharmacology before graduation with M.B.,B.S following which he commenced his surgical training.

He became a Fellow of the Royal College of Surgeon’s of Edinburgh in 1985 and undertook a research fellowship at The Royal Marsden Hospital and Institute of Cancer Research, London between 1998 and 1990. His research involved the development of novel agents for the treatment of advanced prostate cancer. During this period he also collaborated with The University of Maryland and spent three months at Johns Hopkins Hospital in Baltimore and then M.D. Anderson Cancer Centre in Houston Texas. He attained expertise at these centres in Radical Nerve Sparing Prostatectomy and the management of locally advanced prostate cancer in cryo-surgery. He obtained Specialist accreditation in Urology in 1992.

He was appointed Consultant Urological Surgeon at The Royal Surrey County Hospital in 1993. He introduced Radical prostatectomy and Laser prostate surgical techniques to the hospital in association with The St Luke’s Cancer Centre in Guildford. He also introduced the nurse specialist practitioner role in association with the University of Surrey. In 1998, in collaboration with American colleagues from New York and Los Angeles the technique of cryo-surgical ablation for locally advanced and recurrent prostate cancer post radiotherapy was introduced in Guildford. He has a national and international referral base for this technique and many UK surgeons have attended to be trained in this surgical technique. Plans are underway to introduce kidney cryosurgery and High Intensity Focussed Ultrasound (HiFu) for prostate cancer.

He is a tutor on the Endoscopic Surgical training course at The Royal College of Surgeons, London and also lectures at The Institute of Urology Post Graduate Urology Course based at The Middlesex Hospital. He was lead clinician in Urology 1997 to 2002.

Since 2000 he has co-ordinated an active research programme in cryo-surgical treatment for prostate cancer. In 2003 a Research Fellow was appointed in association with The University of Surrey. This programme is on going and the second research fellow is due to be appointed in September 2005.

He is the co-founder of The Prostate Project Charity (1999) an organisation which aids prostate cancer detection awareness based at The Royal Surrey County Hospital and St Luke’s Cancer Centre. The charity incorporated Frimley Park Hospital in 2003 and plans to incorporate The East Surrey Hospital Redhill and the North Hampshire Hospital Basingstoke. The charity to date has raised over £700,000. In 2004 The Prostate Project Foundation Group was formed to support a Chair in Uro-oncology in association with The Post Graduate Medical School in Guildford. This has successfully raised over £500,000 towards this project. It is envisaged that the Chair will commence September 2005.

His leisure interests include Classic Cars and hopes to qualify as a helicopter pilot in 2005. He is married with two children aged 12 and 14. His wife, Janet, is a local magistrate.

Qualifications

Intercalated BSc (Hons) Pharmacology	London	1976
MRCS, LRCP 1979 MB, BS	London	1979
FRCS	Edinburgh	1985
FRCS (Urology)	Edinburgh	1993

Prizes & Awards

1988	Simpla Research Prize (British Association of Urological Surgeons 1988)
1989	Kings Fund Award
1989	Ciba-Geigy Travelling award
1988-1989	Clinical Research Fellow, Royal Marsden Hospital Fulham Road London and Institute of Cancer Research Sutton, Surrey
1982	Anatomy lecturer Southampton Medical School
1997	Ethicon Foundation Fund Travelling Fellowship
1997	Royal College of Surgeons Foundation Inc., New York

Current appointment

Department of Urology Royal Surrey County Hospital and St Luke’s Cancer Centre Guildford Surrey (Appointed December 1993)

Previous Appointments

Pre-Registration

House Surgeon St. Bartholomew’s Hospital London.1.1.80 to 31.7.80

House Physician Enfield District Hospital.1.1.80 to 31.1.81

Post-Registration

Senior House officer St Bartholomew’s Hospital. 1.2.81 to 31.7.81
Neurosurgery

Southampton Surgical SHO Rotation

Senior House Officer Southampton General Hospital 1.8.81 to 31.1.82
Accident and Emergency

Senior House Officer Southampton General Hospital 1.8.81 to 31.1.82
Orthopaedic Surgery

Anatomy Lecturer Southampton University Medical School 1.2.82 to 31.7.82

St James Hospital (Balham) Surgical SHO Rotation

Senior House Officer 1.1.83 to 31.6.83
Urology

Senior House Officer 1.7.83 to 31.12.83
General and Vascular
Surgery

St Richards Hospital (Chichester) Surgical Registrar Rotation

Registrar King Edwards VII Hospital Midhurst 31.1.84 to 30.10.84
Thoracic Surgery

Registrar St Richards Hospital Chichester 1.11.84 to 28.2.84
General and Vascular
Surgery

Registrar St Richards Hospital Chichester 1.3.85 to 30.10.85
General Surgery and
Urology

St Georges Hospital Surgical Registrar Rotation

Registrar Royal Surrey County Hospital Guildford 1.11.85 to 28.2.86
General, Breast and Vascular Surgery

Registrar Royal Surrey County Hospital Guildford 1.3.86 to 31.10.86
Urology

Registrar Royal Surrey County Hospital Guildford 1.11.86 to 30.6.87
General and Colo-Rectal surgery

Registrar Royal Surrey County Hospital Guildford 1.7.87 to 31.10.87
General, Breast and Vascular Surgery

Registrar St. James Hospital Balham London 1.11.87 to 31.12.87
Urology

Urological Research Fellow Royal Marsden Hospital and Institute of Cancer Research London (1.1.88 to 31.8.89)

Locum Senior Registrar Guys Hospital London 1.9.89 to 30.9.89
Urology

Registrar Royal Hampshire Hospital Winchester 1.11.89 to 31.5.90
Urology

St Georges Hospital Senior Urological Registrar Rotation (1.6.90 to 31.03.94)

Senior Registrar St Georges Hospital Tooting London 1.6.90 to 31.12.90

Senior Registrar Royal Surrey County Hospital Guildford1.1.91to 31.12.91

Senior Registrar St Peters Hospital and Institute of Urology London 1.1.92 to 30.9.93
Senior Registrar St Georges Hospital Tooting London 1.10.93 to

Royal Surrey County Hospital Consultant Urological Surgeon April 94 to date

Surgical Courses attended

1984	FRCS course, Whipps Cross Hospital
1986	Anastomoses Work Shop Royal College of Surgeons
1990	Stone Management Course Institute of Urology London
1991	Paediatric Urology Course Cambridge
1991	Andrology Course St Bartholomew’s Hospital London
1991	Spinal Injuries Course Lodge Moor Hospital
1991	Management Course for senior surgical registrars, Royal college of Surgeons London
1992	Laparoscopy course, Kings College Hospital London
1993	Operative Andrology Course St Peters Hospital London
1993	Reconstructive Urology Course St Peters Hospital London
1994	Laser Prostatectomy Course Institute of Urology
1994	Urodynamic Course Institute of Urology
1999	Advanced cryo-ablation techniques Prostate Cancer Los Angeles
2000	Cryo-ablation techniques, Columbia Presbyterian Hospital New York

Publications

Articles

Ahmed S and Davies J. Managing the complications of prostate cryosurgery. BJUI 2005; 95: 480-1.

Ahmed S, Lindsey B and Davies J. Salvage cryosurgery for locally recurrent prostate cancer following radiotherapy. Prostate cancer and Prostatic Disease. (In press).

4-hydroxyandrostenedione in patients with advanced prostatic carcinoma. J.H. Davies, R.J. Shearer, A. Headley, Birt. J. Cancer (1992) 66, 139-142

Environmental carcinogens and their role in urological malignancy. J.H. Davies Urology 92, EUA test, (1992)

Effects of 4-OHA and its metabolites on human prostatic 5 a reductase activity and the androgen receptor. J. H. Davies, R.J. Shearer, M. G. Rowlands, G Poon, J. Houghton, M. Jarman, M. Dowsett

J. Enzyme Inhibition (1992) 6, 141-147.

Hormonal cytoreduction and radiotherapy for carcinoma of the prostate. R.J. Shearer, J. H Davies, J.S.K. Gelister, D.P. Dearnley, Birt. J. Urol. (1992) 69, 521-524.

Microwave hyperthermia: an alternative to prostatectomy for benign prostatic hyperplasia. J.H. Davies medical Society, (1991) 14, 4.

Comparison of aromatase activity in human prostatic, testicular and placental tissues. M. G. Rowlands, J.H. Davies, R.J. Shearer, M Dossett. J. Enzyme Inhibition (1991) 4, 307-313.

Decreasing the risk of Human Immunodeficiency Virus or Hepatitis B Virus infection during endoscopic surgery. J.H. Davies, R. G. Notley, Journal of Urology, (1992) 147-174.

Identification of 4-hydroxyandrostenedione (4-OHA) metabolites in urine by liquid chromatography/mass spectrometry. G. Poon, M. Jarman, R. Mccague, J. H. Davies , C. E. M. Heeremans, R. A, M. van der Hoeven, J. van den Greef. J. Chrom. Bio. Applic. (1992) 576, 235-244.

Should Urologists wear spectacles for TUR? J.H. Davies, G.S.M Harrison. Br. J . Urol (1991) 67 182.183

Aromatase inhibition in advanced prostatic cancer: Preliminary communication. R. J Shearer, J. H. Davies, M. Dowsett, R.C. Coombes. British Journal of Cancer. (1990) 62, 275-276.

Spontaneous rupture of the oesophagus. J H Davies Journal of the Royal Society of Medicine. (1990) 83, case/13.

Effects of 4-hydroxyandrostenedione on 5areductase activity in benign prostatic tissue. J.H. Davies, M.G. Rowlands, R. J. Shearer. The Journal of Urology, (1989) 141, 530a (1460).

In-vitro studies of the effects of 4-hydroxyandrostenedione on androgen metabolism in human benign and malignant tissue. J H Davies, M G Rowlands, M Dowsett, R C Coombes, R J Shearer. Proceedings of the American Association of Cancer Research, (1989) 30, 303a (1204)

Flexible Sigmoidoscopy and double contrast barium enema in the management of patients with large bowel symptoms. R Talbot, J H Davies, C G Marks J Price. Colo-procotology (1988) 10,347-350

Aromatase inhibition in advanced prostatic cancer: A possible new therapeutic pathway. Report of a Phase 1 Study of 4–hydroxyandrostenedione JH Davies, R J Shearer, M Dowsett, P R Malone, A Headley, D Cunningham, R C Coombes. The Journal of Urology, (1998) 141, 500a (1341)

Adenomatoid tumours of the male genial tract. J H Davies, R G Notley, European Urology (1989) 16, 393-394.
Metabolic consequences of forced diuresis following prostatectomy. P R Malone, JH Davies, N J Standfield, R A Bush, J V Gosling, R J Shearer, Brit J Urol. (1986) 58,406-411.

Presentation

Podium

S Ahmed & J Davies. The history and development of cryosurgery. AUA annual congress, San Antonio, 2005

S Ahmed & J Davies. Cryosurgery form the 19th to the 21st century. EAU annual congress, Istanbul, 2005

S Ahmed and J Davies. Cryosurgery: The early days. 3rd International congress on the history of Urology, Vienna, 2004

S Ahmed, B Lindsey, P Sooriakumaran, J Davies. Primary and Salvage cryosurgical ablation of the prostate: early follow-up results. British Prostate Group meeting, London 2004 (Podium)

Bladder exstrophy: long term outcome. J H Davies, C R Woodhouse, American Paediatric Urological Association Washington, 1993.

Long Term outcome of bladder exstrophy: The St Peters Hospital adolescent urology clinic experience. J H Davies, C R Woodhouse, Royal Society of Medicine April 1993.

Radical Radiotherapy: Long term outcome on localised carcinoma of the prostate, AUA, San Antonia, USA 1993. J H Davies R Eels, M Law, I Syndikus, R J Shearer. D P Dearnley.

Environmental carcinogens and their role in urological malignancy, BAUS, June 1992, J H Davies.

Hormonal cytoreduction for acute retention in carcinoma of the prostate. a.SURG Meeting, Cambridge, April 1991. b. British Prostate Group May 1991, J H Davies, R J Shearer.

Emphysematous Pyelonephritis. Section of Urology, Royal Society of Medicine, January 1991. J H Davies, A Vincenti, J Laidlow, G S M Harrison.

Hormonal cytoreduction prior to radiotherapy for cancer of the prostate. a. Guys Research meeting January 1990. b. BAUS, Scarborough 1990. J H Davies, J Gellister, D Dearnley, R J Shearer.

Aromatase inhibition by 4-hydroxyandrostenedione – OHA,CGP 32340 in advanced prostatic cancer. J H Davies, M Dowsett, R C Coombes, R J Shearer.

In-Vitro studies of the effects of 4-hydroxyandrostenedione on androgen metabolism in human prostate and testes. Guys Research meeting January 1989. J H Davies, M G Rowlands, M Dowsett, R J Shearer.

Aromatase Inhibition in Advanced Prostate Cancer. a. British Prostate Group, Taunton May 1988, b.

International Urological Festival, Edingurgh 1989 c. European Assocation of Urology, Amsterdam, 1990. J H Davies, M Dowsett, R C Coombes, R J Shearer.

Spontaneous rupture of the middle and lower oesophagus Wessex Gut Club, November 1989 J H Davies R Rainsbury.

Flexible sigmoidoscopy and double contrast barium enema in the management of patient with large bowel symptoms.1. Toyal Society of Medicine, Section of Colo-proctolgo, Feb88. 2. European Congress of Colo-proctology Geneva.(May 1988). J H Davies, C G Marks

Substernal Gastric Bypass in complicated oesophageal lesions. Association of Surgeons in Training, St Georges Hospital , May 1988 J H Davies R E Sayer.

Poster

S Ahmed, B Lindsey, J Smith and J Davies. A prospective study of the co-morbidities of salvage cryosurgery for the treatment of radiation–failure prostate cancer. BAUS annual meeting, Glasgow, 2005

S Ahmed, B Lindsey and J Davies. Temperature mapping and comparison of the iceball of 3 different cryoprobes for prostate cancer: In vitro study. International Society of Cryosurgery meeting, Crete, 2005

S Ahmed, B Lindsey & J Davies. Cryosurgery as a salvage treatment for locally recurrent prostate cancer following radiotherapy: early single institute experience. EAU annual congress, Istanbul, 2005

S Ahmed, B Lindsey & J Davies. Complications of salvage cryosurgery for the treatment of locally recurrent radiation–failure prostate cancer. EAU annual congress, Istanbul, 2005

S Ahmed, B Lindsey and J Davies. Cryosurgery for prostate cancer: In vitro comparison of the iceball of 3 different freezing probes. Research evening, Royal Surrey County Hospital, Guildford, 2005

S Ahmed & J Davies. Cryosurgery: Applications and current status in urology. XIV International symposium of uro-oncology, Delhi, India, 2004. (Invited speaker).

S Ahmed & J Davies. Cryotherapy: The Coldest Development in Prostate Surgery? BAUS annual meeting, Harrogate, 2004. (Invited speaker).

S Ahmed, B Lindsey, J Davies. Primary and salvage cryosurgical ablation of the prostate: Our early experience. The British Oncological Association annual scientific meeting, Edinburgh, 2004. (Poster).

Preliminary clinicopathological aspects of radical prostatectomy. E P N O’Donoghue, J H Davies, C Parkinson, British Pathology Association, Oxford June 1992.

Environmental carcinogens and their role in urological malignancy. J H Davies, R G Notley, M Coombes, EUA Genoa 1992.

Hormonal cytoreduction for acute retention in carcinoma of the prostate. J H Davies, R J Shearer. British Radiology and Oncology, Brighton April 1991.

Aromatase inhibition in advanced prostate cancer R J Shearer, J H Davies, M Dowsett. 15th International Cancer Congress, Hamburg August 1990.

Hormonal cytoreduction and radiotherapy in prostate cancer European Association of Urology , Amsterdam, June 1990, J H Davies, J Gellister, D Dearnley, R J Shearer.

The pedometer: An objective assessment of the quality of life? European Association Urology, Amsterdam June 1990. J H Davies, P R Malone, R J Shearer.

Aromatase inhibition in advance prostatic cancer. a. EORTC: Second International symposium on “Hormonal manipulation of cancer: peptides, growth factors and new steroidal agents” Rotterdam. April 1990. b. European Association of Urology, Amsterdam, June 1990. J H Davies, M Dowsett, R C Coombes, R J Shearer.

Should urologists wear spectacles for TURP? a. BAUS Scarborough 1990. b. European Association Urology, Amsterdam June 1990. J H Davies, M Harrison

In-vitro studies of the effects of 4-hydroxyandrostenedione on androgen metabolism in human prostate. a. American Association of Cancer Research, San Francisco, May 1989.

British Association of Cancer Research, April 1989. a. Aromatase inhibition in advance prostatic cancer b. The pedometer: an objective assessment of the quality of life. J H Davies, P R Malone, M Dowsett, R J Shearer.

Abstracts

Ahmed S, Lindsey B, Davies J. Primary and salvage cryosurgical ablation of the prostate: Our early experience. Clin Oncol 2004; 16: S43

Ahmed S & Davies J. Cryosurgery form the 19th to the 21st century. Eur Urol (In Press)

Ahmed S, Lindsey B, Davies J. Complications of salvage cryosurgery for the treatment of locally recurrent radiation–failure prostate cancer. Eur Urol (In press)

Ahmed S, Lindsey B, Davies J. Cryosurgery as a salvage treatment for locally recurrent prostate cancer following radiotherapy: early single institute experience. Eur Urol (In press)

Ahmed S, Davies J. The history and development of cryosurgery. J Urol (In press)

Ahmed S, Lindsey B, Smith J, Davies J. A prospective study of the co-morbidities of salvage cryosurgery for the treatment of radiation–failure prostate cancer. BJUI (In press)